Pregnancy protocols need to be updated with scientific research on the microbiome-gut- brain axis. Which protocols? All of them. This includes dietary protocols and Ministry of Health Antenatal Records, charts and so forth. Various branches of medicine, pediatrics, family physicians, gastroenterologists, and so forth need to get up to speed on the microbiome. Analysis, classification, measurement, genomics, machine learning, cross scale modeling, and other techniques are necessary to optimize neonatal microbiomes.